A progestogen is a hormone that acts on the body like progesterone. The term covers both natural progesterone and synthetic versions known as progestins.
In menopausal hormone therapy, a progestogen is often given together with estrogen for people who have a uterus. Estrogen on its own can cause the uterine lining to build up, which raises the risk of uterine cancer, and the progestogen counteracts that effect to protect the lining. The specific type and dose are decided with a prescriber. See the guide on HRT for women and GLP-1 medications.