Menopausal hormone therapy (MHT) — often just called HRT — replaces the estrogen that falls at menopause, usually paired with a progestogen if the uterus is present. It mainly treats menopausal symptoms (hot flashes, night sweats, genitourinary symptoms) and helps protect bone.
MHT is associated with somewhat less visceral fat, but it does not preserve muscle and is not a weight-loss treatment. See the guide on HRT for women and GLP-1 medications.