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Nutrition

Creatine

A naturally occurring compound stored in muscle that helps supply quick energy for lifting; the most-studied sports supplement, sometimes used to support strength and muscle while losing weight.

By the glp1.how editorial teamReviewed

Creatine is a compound your body makes and also gets from meat and fish, stored mostly in muscle where it helps regenerate the quick energy used for short, hard efforts like a set of squats. Supplementing with creatine monohydrate (usually 3–5 g a day) tops up those stores, and it is among the most thoroughly studied sports supplements, with a long track record for supporting strength and training performance in healthy adults.

On a GLP-1 it comes up because the goal is to lose fat while keeping muscle, and creatine can help you get more out of resistance training when appetite and energy are low. It's an aid to training, not a substitute for it or for protein. A small early weight gain from extra water in muscle is normal, and anyone with kidney disease should check with their prescriber first. See supplements on a GLP-1 and why strength training matters.

Source: International Society of Sports Nutrition position stand (external link).

creatinesupplementsmusclestrength-training

Revision history

Updated 1 time since Sep 2, 2026 · show changes
  1. v2

    Body revised

  2. v1

    Change tracking began

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Related terms

  • Resistance training (progressive overload) · Exercise that loads your muscles against resistance and is made gradually harder over time (progressive overload) to keep or build muscle and strength.
  • GLP-1 · A gut hormone (glucagon-like peptide-1) that stimulates insulin release, slows digestion, and reduces appetite; the target of drugs like semaglutide and liraglutide.

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