You may have seen these two sold together in a TikTok Shop "Hack Your Tummy" bundle: Physician's Choice Digestive Enzymes and Physician's Choice 60 Billion Probiotic, both promising less bloating and easier digestion. Post-meal fullness and bloating are common on a GLP-1 because your stomach empties more slowly, so wanting help with them makes sense. We checked the evidence, the ingredient labels and the prices behind both products.
Verdict: Skip (both products)
Composite: 54/100 for each, for the same reasons. Neither product is unsafe, and both target a real GLP-1 complaint (post-meal fullness and bloating). But both put their active ingredients into blends without per-ingredient doses, both lean on factory certifications that sound like product testing but aren't, and both cost more than you need to pay for something you can't check against a study.
Category evidence bar applied: supplement. A top score needs independent human evidence at the product's actual labelled dose.
Digestive Enzymes: what's in it
Each capsule has a 16-enzyme blend totalling 85mg, a separate 159mg prebiotic/probiotic blend (3 Bacillus strains) and a 150mg herbal blend (peppermint, ginger). The label doesn't give the amount of any single enzyme, so all you have is a blend total, with no dose to compare with research.
The one relevant human study we found is a small trial in 16 healthy people: an isolated acid-resistant lipase reduced fullness after a high-fat meal (Levine et al., Gut and Liver, 2015, DOI (external link)). That points in the right direction, and lipase is one of the 16 enzymes here. But it tested a single ingredient at a known dose. It tells you nothing about this 85mg, 16-enzyme mix with unknown amounts of each.
Price: $23.72 one-time / $20.16 on subscription for 60 capsules, as of September 26, 2026.
60 Billion Probiotic: what's in it
The product page advertises "10 probiotic strains" and "60 billion CFU". The Supplement Facts panel does name the strains: ten species, and label copies reprinted by retailers and review sites give strain designations for nine of them (for example L. acidophilus La-14, L. paracasei LPC-37, L. plantarum Lp-115 and B. lactis BL-04). What the label doesn't say is how many CFU each strain contributes. You get only the 60 billion total.
The research on probiotics for gut symptoms is real but modest, and it comes almost entirely from people with irritable bowel syndrome (IBS). A 2026 umbrella review of 27 systematic reviews in IBS found small, mostly low-certainty effects on bloating (Ballena-Caicedo et al., Journal of Clinical Medicine, 2026, DOI (external link)). A separate IBS meta-analysis found larger effects, with very high variability from study to study (Almabruk et al., Cureus, 2024, DOI (external link)). Neither can be matched to this product, because the benefit depends on the strain and the dose of each strain, and the per-strain dose here is unknown.
The most GLP-1-specific source we found is a 2025 review of supplements during GLP-1 treatment, which names fiber and probiotics as options that can help with GI side effects (Johnson et al., Obesity Pillars, 2025, DOI (external link)). It recommends the category in general and didn't study this brand. All four authors list GNC, a supplement retailer, as their affiliation.
Price: as of September 26, 2026, a one-time 30-count bottle is $29.38 and a 60-count bottle is $45.85. Subscriptions use the 60-count bottle and run from $41.27 for one bottle ($0.69/serving) to $110.04 for three ($0.61/serving).
What pushed both scores down
Neither label tells you how much of each active ingredient (or, for the probiotic, each strain) you're getting, so you can't check either formula against the studies above.
The quality claims describe the factory more than the bottle. The brand's Quality & Testing page says its manufacturing partners may hold NSF cGMP certification and use ISO-certified laboratories, and that independent labs, including Eurofins and Light Labs, test its products for purity and potency. Facility certifications cover the manufacturing process, and the company doesn't publish those lab results for you to check. Programs like NSF Certified for Sport or USP Verified independently confirm that a product contains what its label says. Neither product carries that kind of product-level certification.
- "Developed with Doctors®" appears on both. The product page credits a "Scientific Advisory Board" of "8 Physicians, NDs & PhDs" but doesn't name a doctor anywhere we could find.
- Brand history. On April 1, 2021, the FTC sent a warning letter to JB7, LLC, the company that sells Physician's Choice supplements, saying it was unlawfully advertising that its probiotic supplements could treat or prevent COVID-19, based on blog posts on its website. The letter doesn't concern the two products reviewed here, but it was about this same probiotic product line, so it's relevant context.
- Price. We didn't find a dated, like-for-like price comparison we're confident enough to put numbers on. Plain single-ingredient enzyme products and probiotics with a per-strain dose on the label are widely sold, and with those you can check the dose against a study. With these two, the price buys a formula you can't verify.
- The TikTok buzz. Going viral is marketing and says nothing about whether a product works. We couldn't find GLP-1-specific community discussion of either product. The social signal is thin, and public search can't tell a paid or seeded TikTok campaign from organic popularity.
What we didn't find a problem with
Both products use hedged structure/function language ("supports," "helps ease occasional") instead of disease claims, and both carry the required FDA disclaimer. Neither shows a known safety risk at labelled use for a general audience. Both offer a 60-day money-back guarantee and a one-time-purchase option, so you aren't forced into a subscription.
Who it's for
If you want a low-risk, low-effort thing to try for post-meal fullness or bloating and don't mind not knowing your exact doses, these won't hurt you. If your prescriber is already giving you good advice on GI side effects, this doesn't change it.
Who should skip it
Anyone who wants their supplement to match the research. A plain single-ingredient lipase or enzyme product, or a probiotic that lists the dose of each strain, lets you check the label against a study.
What would change the verdict
Per-ingredient doses (per-strain CFU for the probiotic) that match amounts studied in trials, and a product-level third-party certification in place of facility-level claims.
For general strategies that don't involve buying a supplement, see managing nausea on a GLP-1.
This is general education, not medical advice. If bloating or GI discomfort is significant or persistent, talk to your prescriber. It may point to a dose or timing adjustment that a supplement can't replace.
Study findings above are attributed to their authors and were located via PubMed. Prices were checked directly on the vendor's site and are dated above; we don't use affiliate links.