You may have seen these two show up together in a TikTok Shop "Hack Your Tummy" bundle: Physician's Choice Digestive Enzymes and Physician's Choice 60 Billion Probiotic, both promising less bloating and easier digestion. Post-meal fullness and bloating are genuinely common on a GLP-1 — your stomach empties more slowly, so it's a reasonable thing to want help with. Here's what we found when we checked the actual evidence, ingredients, and pricing behind both products.
Verdict: Skip (both products)
Composite: 54/100 for each — same score, same underlying reasons. Neither product is unsafe, and both target a real GLP-1-relevant need (post-meal fullness and bloating). But both blend their active ingredients into undisclosed-dose formulas, lean on facility-level manufacturing certifications that sound like product testing but aren't, and cost roughly twice what a plain, single-ingredient alternative would.
Category evidence bar applied: supplement — independent human evidence at the product's actual labelled dose, needed for a top score.
Digestive Enzymes: what's actually in it
The 16-enzyme blend totals 85mg per capsule, with a separate 159mg prebiotic/probiotic blend (3 Bacillus strains) and a 150mg herbal blend (peppermint, ginger). None of the individual enzyme amounts are disclosed — you get a blend total, not a dose you can check against research.
The one relevant human study we found is a small trial (16 people) showing that an isolated acid-resistant lipase reduced fullness after a high-fat meal (Levine et al., Gut and Liver, 2015, DOI (external link), via PubMed). That's a genuinely encouraging, directionally relevant result — lipase is one of the 16 enzymes in this product — but it's evidence for a single isolated ingredient at a known dose, not for this specific 85mg, 16-enzyme mixture at unknown per-enzyme amounts.
Price: $23.72 one-time / $20.16 on subscription for 60 capsules, as of September 3, 2026.
60 Billion Probiotic: what's actually in it
This one lists "10 probiotic strains" and "60 billion CFU" but doesn't name the strains or say how many CFU each one contributes on the product page — a "Strain Dossier" is referenced but not shown.
The broader evidence for probiotics and GI symptoms is real but modest: a 2026 umbrella review of 27 systematic reviews found small, mostly low-certainty effects on bloating specifically (Ballena-Caicedo et al., , 2026, , via PubMed), while a separate meta-analysis found larger effects but with very high study-to-study variability (Almabruk et al., , 2024, , via PubMed). Neither can be matched to this product, because we don't know which strains are actually in the capsule. What we can say is that probiotics as a category are specifically named as a helpful option for GLP-1-related GI side effects in a recent supplement-guidance review (Johnson et al., , 2025, , via PubMed) — the strongest GLP-1-specific citation we found for either product, though it's a general recommendation, not a study of this brand.