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Polycystic ovary syndrome (PCOS)

A common hormonal condition in women marked by irregular periods, excess androgens, and often insulin resistance and weight gain, and one where GLP-1 medications are increasingly used.

By the glp1.how editorial teamReviewed

Polycystic ovary syndrome (PCOS) is one of the most common hormonal conditions in women of reproductive age. It's diagnosed from a combination of irregular or absent ovulation, signs of excess androgens (such as acne or unwanted hair growth), and polycystic-appearing ovaries on ultrasound. Insulin resistance and weight gain are frequent companions, and they tend to make the hormonal picture worse.

That's why PCOS comes up so often on a GLP-1. Weight loss and improved insulin sensitivity can restore more regular cycles, so fertility can return unexpectedly, and contraception planning matters. In May 2026 a global consensus process backed by 56 academic, clinical, and patient organizations renamed the condition polyendocrine metabolic ovarian syndrome (PMOS) to reflect its hormonal and metabolic nature (Teede et al., The Lancet, 2026, DOI (external link)). A transition period is under way, so you'll still see "PCOS" widely. See the guide on women's health on a GLP-1.

pcoswomens-healthinsulin-resistancefertility

Revision history

Updated 2 times since Sep 2, 2026 · show changes
  1. v3

    Summary rewritten; Body revised

  2. v2

    Body revised

  3. v1

    Change tracking began

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Related terms

  • GLP-1 · A gut hormone (glucagon-like peptide-1) that stimulates insulin release, slows digestion, and reduces appetite; the target of drugs like semaglutide and liraglutide.

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